Author

Olaf Galuba

Novartis (Switzerland)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

Adrienn Volak· 1 shared Álvaro Herrero-NavarroiD· 1 shared Anne‐Christine UldryiD· 1 shared Botond RoskaiD· 1 shared Cameron S. CowaniD· 1 shared Christelle Gasser-Didierlaurant· 1 shared Christian N. ParkeriD· 1 shared Daniel K. BaeschliniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Adrienn Volak

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2 papers

Recent·Most cited

Cell type-focused compound screen in human organoids reveals CK1 and MAPK11 inhibition protects cone photoreceptors from death

Stefan Erich Spirig, Álvaro Herrero-Navarro, Larissa Utz, Valeria J. Arteaga-Moreta, Zoltán Raics, Susana Posada-Céspedes, Stéphanie Chreng, Olaf Galuba, Inga Galuba, Isabelle Claerr, Steffen Renner, Miklos Boldogkoi, Verónica Moreno‐Juan, P. Timo Kleindienst, Adrienn Volak, , Botond Roska

The paper screens 2,707 compounds in human retinal organoids to identify those that protect or damage cone photoreceptors, finding CK1 and MAPK11 inhibitors as protective.

Neuron · Mar 30, 2026Peer-reviewedNeuroscience

Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality control

Lukas‐Adrian Gurzeler, Marion Link, Yvonne Ibig, Isabel Schmidt, Olaf Galuba, Julian Schoenbett, Christelle Gasser-Didierlaurant, Christian N. Parker, Xiaohong Mao, Francis Bitsch, Markus Schirle, Philippe Couttet, Frederic D. Sigoillot, Jana Ziegelmüller, Anne‐Christine Uldry, , Jürgen Reinhardt

The paper introduces two novel readthrough promoters that induce eRF1 degradation, leading to PTC suppression and revealing a new ribosome quality control mechanism.

Cell Reports · Aug 30, 2023Peer-reviewedMolecular Biology