Author

Natália M. Barbosa

Gladstone InstitutesORCID 0000-0002-3952-558XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Fabián Morales-PolancoiD· 2 shared Judith FrydmaniD· 2 shared Ann-Kathrin KöhleriD· 1 shared Ching‐Chieh ChouiD· 1 shared Dan Garza· 1 shared Daniel J. FinleyiD· 1 shared Ekaterina SamatovaiD· 1 shared Elke DeuerlingiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Fabián Morales-PolancoORCID

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2 papers

Recent·Most cited

NAC controls nascent chain fate through tunnel sensing and chaperone action

Jae Ho Lee, Laurenz Rabl, Martin Gamerdinger, Vaishali Goyal, Katrin M. Khakzar, Natália M. Barbosa, Juliana Abramovich, Fabián Morales-Polanco, Ann-Kathrin Köhler, Ekaterina Samatova, Marina V. Rodnina, Elke Deuerling, Judith Frydman

This study identifies NAC's role in regulating translation elongation, cotranslational folding, and organelle targeting through sequence-specific interactions with nascent polypeptides.

Nature · Dec 22, 2025Peer-reviewedBiochemistry

A Comprehensive Enumeration of the Human Proteostasis Network. 1. Components of Translation, Protein Folding, and Organelle-Specific Systems

Overall coordination, Suzanne Elsasser, Lisa P. Elia, Richard I. Morimoto, Evan T. Powers, Daniel J. Finley, Eric Mockler, Leandro de Araújo Lima, Steven M. Finkbeiner, Jason E. Gestwicki, Thomas Stoeger, Kedi Cao, Dan Garza, Jeffery W. Kelly, Miranda Collier, , Judith Frydman

The paper defines and annotates 959 genes comprising the human proteostasis network, focusing on translation, protein folding, and organelle-specific systems.

bioRxiv · Aug 30, 2022 · PreprintBioinformatics