Michael Hahne

This study identifies SLAP as a tumor suppressor that limits SFK activity in colonic epithelial cells, preventing tumorigenesis and hyperproliferation.

The paper shows that pyruvate promotes ciliogenesis in colonic fibroblasts independent of IFT88 and reduces DSS-induced colitis.

This study identifies TTLL6 as a key polyglutamylase in the colon, showing its role in maintaining crypt integrity and preventing colon cancer progression.

The paper uses machine learning to predict drug responses in colorectal cancer cells, identifying novel compounds with cytotoxic or cytostatic effects.

The paper shows that co-translational interactions sort β-catenin mRNAs into distinct polysome populations with different localizations and protein fates.

This study investigates the role of the R2TP chaperone in intestinal stem and progenitor cells, showing its critical function in proliferation and its association with poor colorectal cancer prognosis.