Author
Leiden University Medical CenterORCID 0000-0002-4000-6779Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Sunniva M. K. Bøstrand, Luise A. Seeker, Nadine Bestard-Cuche…·Anna Williams
This study uses snRNAseq to analyze glial cell heterogeneity in Huntington's disease across brain regions, identifying subtype-specific changes and potential mechanisms of glial dysfunction.
Boyd Kenkhuis, Antonios Somarakis, Lynn R.T. Kleindouwel…·Louise van der Weerd
The paper analyzes the co-expression patterns of Iba1, TMEM119, and P2RY12 in microglia from Alzheimer's patients and controls, finding differences in marker combinations associated with disease pathology.
Boyd Kenkhuis, Antonios Somarakis, Lorraine M. de Haan…·Louise van der Weerd
The paper identifies iron-accumulating microglia in Alzheimer's brains, linking iron uptake to microglial activation and disease pathology.
Marjolein Bulk, Boyd Kenkhuis, Linda M. van der Graaf…·Louise van der Weerd
This study shows that iron-sensitive MRI can detect AD pathology distribution patterns in post-mortem brain tissue, with EOAD showing more severe MRI changes.