Author

Bradley L. Hoare

The University of MelbourneORCID 0000-0002-4011-7532Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Arne Christian RuferiD· 1 shared Chunxiao WangiD· 1 shared Daniel FoxiD· 1 shared David A. SykesiD· 1 shared Dmitry B. VeprintseviD· 1 shared Eline J. KoersiD· 1 shared Eric A. Kusznir· 1 shared Erick M. CarreiraiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

Arne Christian RuferORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJun 22, 2026

A complete RXFP1-relaxin interaction model unlocks the design of potent mini-protein modulators

Janik Clément, Tim Lkhagvajargal, Bradley L. Hoare…·Rhys Grinter

This study uses AI to model RXFP1-relaxin interactions and designs potent mini-protein modulators that act as agonists or antagonists.

1 citation

protein structuredeep learning

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Pharmacology & ToxicologyFrontiers in PharmacologyPeer-reviewedApr 9, 2025

A universal cannabinoid CB1 and CB2 receptor TR-FRET kinetic ligand binding assay.

Leire Borrega Roman, Bradley L. Hoare, Miroslav Kosar…·Dmitry B. Veprintsev

This paper develops a TR-FRET-based assay to measure ligand binding kinetics for CB1R and CB2R, finding that D77 enables accurate determination of on- and off-rates for various agonists and antagonists.

5 citations

humanexperimental assay

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