Author

Jennifer A. Rybak

University of Tennessee at KnoxvilleORCID 0000-0002-4017-0456Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

Amita Rani SahooiD· 2 shared Francisco N. BarreraiD· 2 shared Matthias BuckiD· 2 shared Ryan J SchuckiD· 2 shared Adam W. SmithiD· 1 shared Alyssa E. Ward· 1 shared Ioannis SgouralisiD· 1 shared Joshua A. BaccileiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Amita Rani SahooORCID

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2 papers

Recent·Most cited

BiochemistryCommunications BiologyPeer-reviewedMar 11, 2025

Cholesterol inhibits oncogenic EphA2 activation

Ryan J Schuck, Alyssa E. Ward, Amita Rani Sahoo…·Francisco N. Barrera

This study shows that cholesterol inhibits EphA2 self-assembly and oncogenic signaling by preventing its activation through an in-trans mechanism involving protein kinase A.

13 citations

humanproteomics

𝕏 PostBluesky

BiophysicsScience AdvancesPeer-reviewedDec 4, 2024

Phosphatidylinositol (4,5)-bisphosphate drives the formation of EGFR and EphA2 complexes

Pradeep Kumar Singh, Jennifer A. Rybak, Ryan J Schuck…·Adam W. Smith

This study uses PIE-FCCS to show that PIP2 enhances EGFR and EphA2 multimerization in live cells, revealing a role for anionic lipids in RTK interactions.

16 citations

fluorescence / live-cell microscopymicroscopy & imaging analysis

𝕏 PostBluesky