Ryan J Schuck

This study shows that cholesterol promotes ROR1 dimerization and oligomerization in human cells, independent of ligand binding.

This study shows that cholesterol inhibits EphA2 self-assembly and oncogenic signaling by preventing its activation through an in-trans mechanism involving protein kinase A.

This study uses PIE-FCCS to show that PIP2 enhances EGFR and EphA2 multimerization in live cells, revealing a role for anionic lipids in RTK interactions.