Author

Meng-Chen Tsai

Centre National de la Recherche ScientifiqueORCID 0000-0002-4022-9219Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Gilles PagèsiD· 2 shared Alessandra Pierantoni· 1 shared Arthur GouraudiD· 1 shared Barbara H. Garmy-SusiniiD· 1 shared Clément MolinaiD· 1 shared Delphine Marotte· 1 shared Florent MorfoisseiD· 1 shared Frédéric LucianoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Gilles PagèsORCID

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2 papers

Recent·Most cited

Exploiting De Novo Serine Synthesis as a Metabolic Vulnerability to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma

Manon Teisseire, Umakant Sahu, Julien Parola, Meng‐Chen Tsai, Valérie Vial, Jérôme Durivault, Renaud Grépin, Yann Cormerais, Clément Molina, Arthur Gouraud, Gilles Pagès, Issam Ben‐Sahra, Sandy Giuliano

This study identifies serine synthesis as a metabolic vulnerability in sunitinib-resistant renal cell carcinoma, showing that inhibiting key enzymes enhances drug sensitivity.

Cancer Research · Mar 3, 2025Peer-reviewedCancer Biology

Comparative effects of proton and photon irradiation on the molecular and cellular profiles of triple-negative breast cancer: the crucial impact of VEGFC on tumor microenvironment remodeling

Saharnaz Sarlak, Delphine Marotte, Florent Morfoisse, Alessandra Pierantoni, Jessy Sirera, Meng-Chen Tsai, Marie Vidal, Joël Hérault, Barbara H. Garmy-Susini, J. Doyen, Frédéric Luciano, Gilles Pagès

This study compares the effects of proton and photon irradiation on TNBC tumor microenvironment, finding that X-irradiated tumors are more aggressive and VEGFC inhibition reduces proliferation.

bioRxiv · Aug 19, 2024 · PreprintCancer Biology