Jérôme Durivault

This study shows MMRi62 induces iron depletion-driven apoptosis in medulloblastoma cells without requiring ferritin degradation or ferroptosis.

This study shows that deleting ferritin heavy chain in medulloblastoma cells limits tumor growth by promoting iron-dependent stress and sensitizing cells to iron toxicity.

This study shows glucocorticoids increase P-body numbers and alter mRNA translation fate based on transcript sequence features, not abundance.

This study identifies serine synthesis as a metabolic vulnerability in sunitinib-resistant renal cell carcinoma, showing that inhibiting key enzymes enhances drug sensitivity.