Author

Valérie Vial

Scientific Centre of MonacoORCID 0000-0002-8423-4167Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Jérôme DurivaultiD· 3 shared Fabien Segui· 2 shared Marina PagnuzziiD· 2 shared Milica VučetićiD· 2 shared Vincent PiccoiD· 2 shared Yann CormeraisiD· 2 shared Annael BerniniiD· 1 shared Arthur GouraudiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

Jérôme DurivaultORCID

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3 papers

Recent·Most cited

MMRi62 induces iron depletion-driven apoptosis through a ferritin-independent mechanism

Fabien Segui, Marina Pagnuzzi, Julie Antiq, Jérôme Durivault, Valérie Vial, Nicolas Bogliotti, Isabelle Leray, Milica Vučetić, Vincent Picco

This study shows MMRi62 induces iron depletion-driven apoptosis in medulloblastoma cells without requiring ferritin degradation or ferroptosis.

bioRxiv · Sep 23, 2026 · PreprintCancer Biology

Deletion of Ferritin Heavy Chain Limits Tumor Growth and Promotes Iron-Dependent Stress in Medulloblastoma

Fabien Segui, Jérôme Durivault, Marina Pagnuzzi, Valérie Vial, Annael Bernini, Doria Filipponi, 武士原山, Pauline Perne, Delphine Debayle, Kévin Müller, Eddy Pasquier, Marion Le Grand, Scott K. Parks, Yann Cormerais, Jacques Pouysségur, , Vincent Picco

This study shows that deleting ferritin heavy chain in medulloblastoma cells limits tumor growth by promoting iron-dependent stress and sensitizing cells to iron toxicity.

bioRxiv · Jul 25, 2026 · PreprintCancer Biology

Exploiting De Novo Serine Synthesis as a Metabolic Vulnerability to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma

Manon Teisseire, Umakant Sahu, Julien Parola, Meng‐Chen Tsai, Valérie Vial, Jérôme Durivault, Renaud Grépin, Yann Cormerais, Clément Molina, Arthur Gouraud, Gilles Pagès, Issam Ben‐Sahra, Sandy Giuliano

This study identifies serine synthesis as a metabolic vulnerability in sunitinib-resistant renal cell carcinoma, showing that inhibiting key enzymes enhances drug sensitivity.

Cancer Research · Mar 3, 2025Peer-reviewedCancer Biology