Oliver Tüscher

Network Adaptability Governs Resilience and Susceptibility to Social Defeat

The paper investigates resilience and susceptibility to social defeat stress in mice using brain imaging, identifying structural and network-level differences associated with coping mechanisms.

Boredom and the representation of information content in the neocortex

This study investigates how the brain represents information content in sensory experience and links it to boredom-related behavior across humans and mice.

TACR3 variant confers resilience to aging and Alzheimer's disease

This study identifies the TACR3 variant rs2765 as protective against age- and Alzheimer's-related cognitive decline, showing slower cognitive decline and younger epigenetic age in carriers.

16p11.2 Copy Number Variation Alters Genome Architecture and Transcriptional Regulation During Neurodevelopment

This study investigates how 16p11.2 copy number variations affect genome architecture and transcription during neurodevelopment, finding both local dosage effects and broader chromatin changes.

A ventral striatal learning signal reflecting individual differences in the success of fear extinction

The paper identifies two extinction learning trajectories using LCGM and finds ventral striatal activity patterns linked to extinction success.

A mathematical model of the Alzheimer's Disease biomarker cascade demonstrates statistical pitfalls in identifying neurobiological surrogates of cognitive reserve

The paper demonstrates that ignoring sampling time points in statistical analyses can lead to misinterpretation of interaction effects between biomarkers and cognitive reserve in Alzheimer's Disease.

Right Inferior Frontal Gyrus Mediates Emotion-Cognition Interaction viaFrequency-Specific Top-Down Modulation

This study identifies frequency-specific top-down modulation in the right inferior frontal gyrus (rIFG) during emotion-cognition interaction using EEG and source reconstruction in a large human cohort.

Information theoretic evidence for layer- and frequency-specific changes in cortical information processing under anesthesia

This paper introduces a spectrally-resolved measure of active information storage to analyze how anesthesia affects cortical information processing, finding frequency- and layer-specific changes in information storage.

Trait salivary alpha-amylase activity levels define the conditions for facilitation by L-DOPA of extinction consolidation

The paper examines how L-DOPA affects extinction memory consolidation and finds that its benefits depend on baseline salivary alpha-amylase levels.

Network efficiency predicts resilience to cognitive decline in elderly at risk for Alzheimer's

This study finds that higher white matter network efficiency is associated with greater resilience to cognitive decline in elderly individuals, independent of amyloid and tau pathology.

Cortical network mechanisms of response inhibition

This study investigates the functional roles of rIFG and pre-SMA in response inhibition using MEG/fMRI, finding rIFG precedes pre-SMA activity and drives connectivity predicting stopping performance.

Measuring spectrally-resolved information transfer for sender- and receiver-specific frequencies

The paper introduces a method to measure frequency-specific information transfer in neural systems and finds complex spectral patterns in human MEG and ferret brain recordings.

Community driven dynamics of oscillatory network responses to threat

The paper analyzes dynamic network responses to threat, showing that community reorganization and flexibility drive physiological responses.

A Combined Behavioral and Neuroimaging Battery to Test Positive Appraisal Style Theory of Resilience in Longitudinal Studies

The paper presents a combined behavioral and fMRI battery to assess positive appraisal style theory of resilience in longitudinal studies, showing replicable results in healthy subjects.

Excitability regulation in the dorsomedial prefrontal cortex during sustained instructed fear responses: a TMS-EEG study

This study uses TMS-EEG to examine dmPFC excitability during fear processing and links it to structural brain properties.