Nicholas W. Harper

The paper uses peptide tiling to identify viral protein regions that modulate stress-induced cell death in U2OS cells, revealing modular regulatory functions.

This study identifies genetic dependencies of cell death following EGFR inhibition by analyzing functional genomics data.

The paper shows that loss of Pol II protein, specifically Rbp1, triggers apoptosis independently of transcriptional loss, revealing a new apoptotic response mechanism contributing to cancer therapy efficacy.

This study shows calcineurin (CN) helps yeast adapt to chronic stress through two distinct mechanisms involving Crz1 and Crz1-independent pathways.

The paper introduces multi-CUT&Tag, a method to simultaneously map multiple chromatin proteins in single cells, revealing co-localization and cell-type-specific chromatin features.