Gavin A Birdsall

Peptide tiling across viral proteomes identifies modular regulators of stress-induced cell death

The paper uses peptide tiling to identify viral protein regions that modulate stress-induced cell death in U2OS cells, revealing modular regulatory functions.

Genome-wide profiling identifies the genetic dependencies of cell death following EGFR inhibition

This study identifies genetic dependencies of cell death following EGFR inhibition by analyzing functional genomics data.

Pol II degradation activates cell death independently from the loss of transcription

The paper shows that loss of Pol II protein, specifically Rbp1, triggers apoptosis independently of transcriptional loss, revealing a new apoptotic response mechanism contributing to cancer therapy efficacy.