Megan E. Honeywell

This study identifies genetic dependencies of cell death following EGFR inhibition by analyzing functional genomics data.

The paper shows that loss of Pol II protein, specifically Rbp1, triggers apoptosis independently of transcriptional loss, revealing a new apoptotic response mechanism contributing to cancer therapy efficacy.

The paper shows that different bacteria modulate tamoxifen toxicity in C. elegans through fatty acid metabolism, with varying death mechanisms and FA profiles.

This study quantifies drug-induced growth inhibition and cell death using live/dead cell counting and introduces drug GRADE to analyze their relationship, revealing drug- and genotype-specific responses.

The paper identifies antagonistic drug interactions in cancer therapy by analyzing death activation kinetics, finding that single agent dominance occurs due to differences in cell death onset time.