Author

Mercedes Gonzalez Juarrero

Colorado State UniversityORCID 0000-0002-4045-2365Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Anne J. M. Lenaerts· 2 shared Bernd MeibohmiD· 2 shared Firat KayaiD· 2 shared Gregory T. RobertsoniD· 2 shared Jiuyu LiuiD· 2 shared Matthew D. ZimmermaniD· 2 shared Michelle M. ButleriD· 2 shared Richard E. Lee Jr.iD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Anne J. M. Lenaerts

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2 papers

Recent·Most cited

Sterilizing activity of spectinamide MBX-4888A when replacing linezolid in the Nix-TB regimen in the relapsing BALB/c mouse model of tuberculosis

Nathan Peroutka‐Bigus, Michael S. Sherman, Firat Kaya, Samanthi L. Waidyarachchi, Jiuyu Liu, Joel N. Rushefsky, Michelle M. Butler, Terry L. Bowlin, Bernd Meibohm, Mercedes Gonzalez Juarrero, Anne J. M. Lenaerts, Matthew Zimmerman, Richard E. Lee Jr., Gregory T. Robertson

This study evaluates replacing linezolid with spectinamide MBX-4888A in the Nix-TB regimen for tuberculosis in a mouse model, showing potential for reduced adverse effects.

Antimicrobial Agents and Chemotherapy · Sep 30, 2025Peer-reviewedMicrobiology

Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis

Allison A. Bauman, Jansy Passiflora Sarathy, Firat Kaya, Lisa M. Massoudi, Michael S. Scherman, Courtney Hastings, Jiuyu Liu, Min Xie, Elizabeth J. Brooks, Michelle E. Ramey, Isabelle L. Jones, Noalani D. Benedict, Madelyn R. Maclaughlin, Jake A. Miller-Dawson, Samanthi L. Waidyarachchi, , Gregory T. Robertson

This study shows that MBX-4888A, a spectinamide, shortens tuberculosis treatment in murine models by improving tissue distribution and working well with rifampin and pyrazinamide.

Antimicrobial Agents and Chemotherapy · Sep 30, 2024Peer-reviewedMicrobiology