Author

Michelle M. Butler

Microbiotix (United States)ORCID 0009-0003-2850-4841Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Microbiology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:mouse· 2

Frequent Co-Authors

Terry L. BowliniD· 3 shared Anne J. M. Lenaerts· 2 shared Bernd MeibohmiD· 2 shared Firat KayaiD· 2 shared Gregory T. RobertsoniD· 2 shared Jiuyu LiuiD· 2 shared Matthew D. ZimmermaniD· 2 shared Mercedes Gonzalez JuarreroiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

Terry L. BowlinORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

trans-Translation inhibitors that kill M. tuberculosis and pathogenic Non-tuberculous Mycobacteria have a dual mechanism of action

Akanksha Varshney, Ziyi Jia, Gebremichal Gebretsadik, Narendran G-Dayanandan, Terry L. Bowlin, Michelle M. Butler, Anthony D. Baughn, Kenneth C. Keiler

The paper identifies acylaminooxadiazole derivatives that kill mycobacteria by inhibiting trans-translation and disrupting iron homeostasis.

bioRxiv · Jan 22, 2026 · PreprintMicrobiology

Sterilizing activity of spectinamide MBX-4888A when replacing linezolid in the Nix-TB regimen in the relapsing BALB/c mouse model of tuberculosis

Nathan Peroutka‐Bigus, Michael S. Sherman, Firat Kaya, Samanthi L. Waidyarachchi, Jiuyu Liu, Joel N. Rushefsky, Michelle M. Butler, Terry L. Bowlin, Bernd Meibohm, Mercedes Gonzalez Juarrero, Anne J. M. Lenaerts, Matthew Zimmerman, Richard E. Lee Jr., Gregory T. Robertson

This study evaluates replacing linezolid with spectinamide MBX-4888A in the Nix-TB regimen for tuberculosis in a mouse model, showing potential for reduced adverse effects.

Antimicrobial Agents and Chemotherapy · Sep 30, 2025Peer-reviewedMicrobiology

Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis

Allison A. Bauman, Jansy Passiflora Sarathy, Firat Kaya, Lisa M. Massoudi, Michael S. Scherman, Courtney Hastings, Jiuyu Liu, Min Xie, Elizabeth J. Brooks, Michelle E. Ramey, Isabelle L. Jones, Noalani D. Benedict, Madelyn R. Maclaughlin, Jake A. Miller-Dawson, Samanthi L. Waidyarachchi, , Gregory T. Robertson

This study shows that MBX-4888A, a spectinamide, shortens tuberculosis treatment in murine models by improving tissue distribution and working well with rifampin and pyrazinamide.

Antimicrobial Agents and Chemotherapy · Sep 30, 2024Peer-reviewedMicrobiology