Author

Liang Qu

Shanghai Medical College of Fudan UniversityORCID 0000-0002-4063-2972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:multiome· 1

Frequent Co-Authors

Haomeng Kou· 2 shared Jie YiniD· 2 shared Qian Pan· 2 shared Xinyuan Liao· 2 shared Xinyue WangiD· 2 shared Yanyan WangiD· 2 shared Chenchen ZhangiD· 1 shared Chengzhi ZhaoiD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersImmunology

Haomeng Kou

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CircRNA-based, non-integrated, in vivo panCAR-mediated B cell immune resetting in mouse models and non-human primates

Yanyan Wang, Xinyue Wang, Qian Pan, Haomeng Kou, Chi Zhang, Shengnan She, Jie Yin, Xinyuan Liao, Wanjia Wang, Ligaoyue Zhang, Huji Xu, Tianlei Ying, Yanling Wu, Liang Qu

This paper develops circRNA-based in vivo panCAR to achieve comprehensive B cell depletion and reconstitution, showing efficacy in treating B cell disorders and aging in mice and non-human primates.

bioRxiv · Aug 11, 2025 · PreprintImmunology

Synergically enhanced anti-tumor immunity of in vivo CAR by circRNA vaccine boosting

Yanyan Wang, Liangru Lin, Xinyue Wang, Jing Li, Qian Pan, Haomeng Kou, Jie Yin, Fei Gao, Xinyuan Liao, Chenchen Zhang, Qimeng Yin, Chengzhi Zhao, Xinyang Li, Jinzhong Lin, Yichi Xu, , Liang Qu

This study develops circRNA-based in vivo CAR and vaccines that synergistically enhance anti-tumor immunity in mice.

Cell Reports Medicine · Jul 24, 2025Peer-reviewedImmunology

Leveraging Endogenous ADAR for Programmable Editing on RNA

Liang Qu, Zongyi Yi, Shiyou Zhu, Chunhui Wang, Zhongzheng Cao, Zhuo Long Zhou, Pengfei Yuan, Ying Fang Yu, Feng Tian, Zhiheng Liu, Ying Bao, Yanxia Zhao, Wensheng Wei

This paper introduces LEAPER, a method using endogenous ADAR proteins for targeted RNA editing, demonstrating its efficacy in restoring p53 function and catalytic activity in disease models.

bioRxiv · Apr 19, 2019 · PreprintGenomics