Author

John Ross Crawford

Children's Hospital of Orange CountyORCID 0000-0002-4100-7001Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron Timothy GriffiniD· 1 shared Adolfo SequeiraiD· 1 shared Aleksandar ObradovićiD· 1 shared Alexis De La Rosa· 1 shared Amanda Wilson· 1 shared Andrea CalifanoiD· 1 shared Anna Virovka· 1 shared Bing ReniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSystems Biology

Aaron Timothy GriffinORCID

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2 papers

Recent·Most cited

UC Irvine Brain Initiative Cell Atlas Network (BICAN) Brain Procurement Program for the Center for Multiomic Human Brain Cell Atlas Project

Jillian V. Berry, Bryan M Tran, Ginny Wu, Zhiqun Tan, Elizabeth Mendoza, Miyoung Kim, Zeynep Arat, Payton Sho Huai Lin, Lorena Valenzuela, Todd C. Holmes, Anna Virovka, Melina Thaxton, Matthew Nguyen, Sabrina Stein, Victoria Raha Sigaroudi, , Xiangmin Xu

The paper describes a multi-institutional program for collecting neurotypical human brains to support multiomic brain cell atlas studies, highlighting challenges and opportunities for donor recruitment.

bioRxiv · Dec 26, 2025 · PreprintNeuroscience

Elucidation and Pharmacologic Targeting of Master Regulator Dependencies in Coexisting Diffuse Midline Glioma Subpopulations

Ester Calvo Fernández, Lorenzo Tomassoni, Xu Zhang, Junqiang Wang, Aleksandar Obradović, Pasquale Laise, Aaron Timothy Griffin, Lukas J. Vlahos, Hanna E. Minns, Diana V. Morales, Christian Simmons, Matthew Gallitto, Hong-Jian Wei, Timothy J. Martins, Pamela Sue Becker, , Jovana Pavisic

The paper identifies master regulator dependencies in coexisting diffuse midline glioma subpopulations and shows that combination therapy targeting these regulators improves survival in vivo.

bioRxiv · Mar 17, 2024 · PreprintSystems Biology