Yi‐Chin Toh

Dissecting Immune-Epithelial Interactions in Airway Infection at Single-Cell Resolution Using a Compartmentalised Microfluidic Device

The paper introduces a microfluidic device with machine learning analysis to study immune-epithelial interactions during airway infection, revealing distinct immune cell behaviors under RSV infection and therapeutic intervention.

From Fabrication to Flow: Impact of Print Orientation on Surface Qualities and Capillary-Driven Flow in Laser SLA-based Open Microchannels

This study evaluates how print orientation affects surface texture and capillary-driven flow in laser SLA-printed microchannels, finding that surface tortuosity, not roughness, better predicts flow behavior.

From Home to Transcriptome: Comparing the transcriptomic profile of induced immune response via lipopolysaccharide stimulation in homeRNA and venous blood

This study compares the transcriptomic profiles of LPS-induced immune responses in homeRNA and venous blood samples, showing homeRNA captures comparable inflammatory responses.

Suspended Tissue Engineering with Assemblable Microfluidics (STEAM)

The paper introduces STEAM, a microfluidic platform for creating suspended tissue constructs with spatial patterning and mechanical manipulation capabilities, demonstrating its use in engineered muscle tissue.

A Patient-Specific 3D Printed Carotid Artery Model Integrating Vascular Structure, Flow and Endothelium Responses

This paper develops a patient-specific 3D printed carotid artery model that integrates vascular structure, flow, and endothelial responses to study atherosclerosis.

Simulating big mechanically-active culture systems (BigMACS) using paired biomechanics-histology FEA modelling to derive mechanobiology design relationships.

This study introduces a biomechanics-histology FEA framework to simulate BigMACS and derive mechanobiology design relationships for controlling cell behavior and tissue patterning.

FEZ1 participates in human embryonic brain development by modulating neuronal progenitor subpopulation specification and migration

This study shows FEZ1 is essential for human brain development by regulating neuronal progenitor subpopulations and migration, with its deletion causing abnormalities in cortical layer formation.