Fatty acid synthesis supports tumor progression through keeping TORC1 receptive for Insulin/PI3K signaling
Dorottya Károlyi, Balint Solyom Botor, Natali Neuhauser, András Rubics, Janka Szinyákovics, Tibor Kovács, Mária Péter, Gabor E. Balogh, Fergal O’Farrell, Szabolcs Takáts
The paper shows that fatty acid synthesis supports tumor progression by maintaining TORC1 sensitivity to Insulin/PI3K signaling through ACC-dependent mechanisms.
Cell Death and Disease · Apr 10, 2026Peer-reviewedCell Biology