Szabolcs Takáts

Autophagy promotes tumor growth through facilitating JAK/STAT signaling in a lysosomal degradation independent manner

This study shows that autophagy promotes tumor growth by enhancing JAK/STAT signaling independently of lysosomal degradation in Drosophila models.

Fatty acid synthesis supports tumor progression through keeping TORC1 receptive for Insulin/PI3K signaling

The paper shows that fatty acid synthesis supports tumor progression by maintaining TORC1 sensitivity to Insulin/PI3K signaling through ACC-dependent mechanisms.

Huntington's disease-associated ankyrin repeat palmitoyl transferases are rate-limiting factors in lysosome formation and fusion

This study identifies Hip14 and Patsas as rate-limiting factors in lysosome formation and fusion, linking defective palmitoylation to Huntington's disease-like symptoms in Drosophila.

The GTPase-activating protein CG42795 is a potent neuronal regulator of ageing in Drosophila melanogaster

This study identifies CG42795 as a neuronal GTPase-activating protein that enhances autophagy, locomotor ability, and lifespan in Drosophila, with conserved effects in human cells.