Author

Shehab Ismail

KU LeuvenORCID 0000-0002-4150-1077Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:protein sequence· 1

Frequent Co-Authors

Alison G. TeboiD· 1 shared Arnela DautbasiciD· 1 shared Atanasio Gómez‐MulasiD· 1 shared Daniel AbankwaiD· 1 shared Desiree Isabella FrecotiD· 1 shared Elisabeth Schaffner‐ReckingeriD· 1 shared Hanne PeetersiD· 1 shared Matthew James SmithiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Alison G. TeboORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NanoBlocks: creating fluorescent biosensors from affinity binders using competitive binding

Silke Denis, Vincent M.L. Van Deuren, Desiree Isabella Frecot, Ulrich Rothbauer, Shehab Ismail, Alison G. Tebo, Peter Dedecker

This paper introduces NanoBlocks, a method to convert affinity binders into fluorescent biosensors by adding competitive peptides, demonstrating their use in detecting targets in vitro and in cells.

ACS Nano · Oct 29, 2026Peer-reviewedBiochemistry

Development of a genetically encoded and potent PDE6D inhibitor

Atanasio Gómez‐Mulas, Elisabeth Schaffner‐Reckinger, Hanne Peeters, Rohan Chippalkatti, Arnela Dautbasic, Matthew James Smith, Shehab Ismail, Daniel Abankwa

This study develops a genetically encoded PDE6D inhibitor, SNAP-STI, which shows higher potency than small molecule inhibitors but does not effectively inhibit K-Ras membrane anchorage or MAPK signaling.

ChemBioChem · Nov 18, 2025Peer-reviewedBiochemistry