Alison G. Tebo

This paper introduces NanoBlocks, a method to convert affinity binders into fluorescent biosensors by adding competitive peptides, demonstrating their use in detecting targets in vitro and in cells.

WHaloForce is a chemigenetic tension sensor that images molecular forces in living cells and animals, revealing tissue-specific force patterns and ovulation-related molecular loading.

This paper develops an improved FBP sensor, HYlight2, for in vivo imaging of glycolysis in various organisms.

The paper develops two variants of a glutamate indicator with enhanced sensitivity and tailored deactivation rates for studying synaptic transmission in vivo.

This paper introduces two new far-red fluorescent GECIs, FR-GECO1a and FR-GECO1c, characterized for their Ca2+ sensitivity and performance in neuronal imaging.

The paper introduces nirFAST, a tunable NIR fluorescent reporter for multiplexed imaging, enabling subdiffraction resolution and cell cycle monitoring in live cells.

This paper introduces FABCON, a tool for detecting lipid droplet-organelle contact sites in living cells, showing their dynamic behavior under different metabolic conditions.

The paper develops T-GECO1, a blue-shifted genetically encoded Ca2+ indicator with enhanced two-photon brightness for improved neuronal activity imaging.

The paper develops novel fluorogens that activate FAST proteins and convert splitFAST systems into chemical dimerizers, reducing the need for protein engineering.

The paper engineers a fluorescent chemogenetic reporter with tunable color for live-cell imaging, enabling advanced spectral control and compatibility with advanced imaging techniques.

The paper introduces two spectrally orthogonal chemogenetic tags for multicolor live cell imaging, enabling detection of early cell cycles and protein interactions.

This paper introduces frFAST, a far-red fluorescent protein that enables high-contrast imaging in live organisms and facilitates the design of chemogenetic reporters for protein interactions.