Joeri J. Meijsen

Trans-Ancestry GWAS of Hot Flashes Reveals Potent Treatment Target and Overlap with Psychiatric Disorders

This paper conducts a trans-ancestry GWAS of hot flashes, identifies TACR3 as a key genetic target, and finds genetic overlaps with psychiatric disorders.

Population-based Risk of Psychiatric Disorders Associated with Recurrent CNVs

The paper estimates population-based risks of psychiatric disorders associated with 34 recurrent CNVs using a large case-cohort sample, finding moderate risks for ADHD, autism, and schizophrenia, but not depression.

PA-FGRS is a novel estimator of pedigree-based genetic liability that complements genotype-based inferences into the genetic architecture of major depressive disorder

The paper introduces PA-FGRS, a method to estimate genetic liability from family records, and shows it improves MDD classification and GWAS power when combined with genotypes.

Publicly Available Privacy-preserving Benchmarks for Polygenic Prediction

This paper presents a publicly available privacy-preserving benchmark for polygenic prediction using summary-level data, enabling accurate model performance estimation without access to individual-level genetic data.

Analysis of Polygenic Score Usage and Performance in Diverse Human Populations

The paper analyzes polygenic score usage and performance across diverse human populations, finding significant disparities in effect sizes and highlighting the need for more inclusive GWAS.