Author

Zachary Ingram

University of PittsburghORCID 0000-0002-4175-8665Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. N. EngelmaniD· 1 shared Alexandra K. Hughson· 1 shared Barbie K. Ganser‐PornillosiD· 1 shared Christopher E. KlineiD· 1 shared Gregory A. SowdiD· 1 shared Hannah L. FischeriD· 1 shared Melissa KaneiD· 1 shared Nayara F. B. dos SantosiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

A. N. EngelmanORCID

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1 paper

Recent·Most cited

Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration

Zachary Ingram, Christopher E. Kline, Alexandra K. Hughson, Parmit Kumar Singh, Hannah L. Fischer, Rajalingham Radhakrishnan, Gregory A. Sowd, Nayara F. B. dos Santos, Barbie K. Ganser‐Pornillos, Simon C. Watkins, Melissa Kane, A. N. Engelman, Zandrea Ambrose

This study shows that sequential binding of CypA and CPSF6 to HIV-1 capsid is necessary for nuclear entry and integration, and that lenacapavir targets this process.

mBio · Feb 27, 2025Peer-reviewedMicrobiology