Author
University of UtahORCID 0000-0002-1353-4613Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Nayara F. B. dos Santos, Jacob A. Lewis, Mason Hansen…·Owen Pornillos
This study shows lenacapavir remodels HIV-1 capsid structure by altering non-covalent interactions and material properties, leading to capsid rupture and impaired viral replication.
Zachary Ingram, Christopher E. Kline, Alexandra K. Hughson…·Zandrea Ambrose
This study shows that sequential binding of CypA and CPSF6 to HIV-1 capsid is necessary for nuclear entry and integration, and that lenacapavir targets this process.
Randall T. Schirra, Nayara F. B. dos Santos, Barbie K. Ganser‐Pornillos, Owen Pornillos
The paper shows that Arg18 substitutions in HIV-1 capsid protein lead to non-fullerene capsid assembly with unique structural features.