Author

Hannah L. Fischer

University of PittsburghORCID 0000-0002-8267-6308Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:electronic health records· 1

Frequent Co-Authors

Simon C. WatkinsiD· 2 shared Zandrea AmbroseiD· 2 shared A. N. EngelmaniD· 1 shared Alexandra K. Hughson· 1 shared Barbie K. Ganser‐PornillosiD· 1 shared Christopher E. KlineiD· 1 shared Christopher Kline· 1 shared Gregory A. SowdiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Simon C. WatkinsORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintMay 20, 2025

Deletion of the Envelope gene attenuates SARS-CoV-2 infection by altered Spike localization and increased cell-to-cell transmission

Hannah L. Fischer, Shanmugapriya Shanmugapriya, Christopher Kline…·Zandrea Ambrose

This study shows that deleting the Envelope gene in SARS-CoV-2 increases cell surface Spike protein and cell-to-cell transmission, reducing neutralizing antibody inhibition.

1 citation

humanelectronic health records

𝕏 PostBluesky

MicrobiologymBioPeer-reviewedFeb 27, 2025

Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration

Zachary Ingram, Christopher E. Kline, Alexandra K. Hughson…·Zandrea Ambrose

This study shows that sequential binding of CypA and CPSF6 to HIV-1 capsid is necessary for nuclear entry and integration, and that lenacapavir targets this process.

17 citationstop 4%

humanexperimental assay

𝕏 PostBluesky