Alan M Smith

Genome-wide chromatin accessibility during early embryogenesis in a generalist cichlid fish

This study maps genome-wide chromatin accessibility in A. calliptera embryos across three stages, revealing dynamic changes in regulatory elements and transcription factor activity during early development.

Evolution of chromatin accessibility associated with traits of cichlid phenotypic diversity

This study links chromatin accessibility divergence to phenotypic diversity in cichlid fishes by analyzing ATAC-seq and transcriptomes across multiple tissues and species.

Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes

The paper investigates the dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes, revealing expanded piwil1 genes and divergent piRNA-producing loci.

oca2 targeting using CRISPR/Cas9 in the Malawi cichlid Astatotilapia calliptera

This study uses CRISPR/Cas9 to edit the oca2 gene in Astatotilapia calliptera, demonstrating efficient germline transmission and phenotypic effects on melanin synthesis.