This study links chromatin accessibility divergence to phenotypic diversity in cichlid fishes by analyzing ATAC-seq and transcriptomes across multiple tissues and species.

bioRxiv · Oct 9, 2025 · PreprintEvolutionary Biology

The genome sequence of the Violet Carpenter Bee, Xylocopa violacea (Linnaeus, 1785): a hymenopteran species undergoing range expansion.

Will J. Nash, Angela Man, Seanna J. McTaggart, Kendall Baker, Tom Barker, Leah Catchpole, Alex Durrant, Karim Gharbi, Naomi Irish, Gemy Kaithakottil, Debby Ku, Aaliyah Providence, Felix Shaw, David Swarbreck, Chris Watkins, , Wilfried Haerty

The paper presents a reference genome assembly for the Violet Carpenter Bee, including gene annotation and mitochondrial genome, as part of the European Reference Genome Atlas.

Heredity · Sep 15, 2024Peer-reviewedGenomics

Chromatin accessibility associated with aquaculture relevant traits in tilapia

Tarang K. Mehta, Angela Man, Adam Ciezarek, Keith Ranson, David James Penman, Federica Di Palma, Wilfried Haerty

The paper identifies regulatory variants associated with aquaculture traits in tilapia using ATAC-seq and genetic data.

bioRxiv · Feb 17, 2023 · PreprintGenomics

Long read sequencing reveals novel isoforms and insights into splicing regulation during cell state changes

David J. Wright, Nicola Hall, Naomi Irish, Angela Man, Will Glynn, Arne W. Mould, Alejandro De Los Angeles, Emily Angiolini, David Swarbreck, Karim Gharbi, Elizabeth M. Tunbridge, Wilfried Haerty

The paper uses long-read sequencing to identify novel isoforms and splicing regulators during neuronal differentiation in human neuroblastoma cells.

BMC Genomics · Jan 10, 2022Peer-reviewedGenomics

Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients

Alfonsina D’Amato, Lorenzo Di Cesare Mannelli, Elena Lucarini, Angela Man, Gwénaëlle Le Gall, Jacopo Junio Valerio Branca, Carla Ghelardini, Amedeo Amedei, Eugenio Bertelli, Marì Regoli, Alessandra Pacini, Giulia Luciani, Pasquale Gallina, Annalisa Altera, Arjan Narbad, , Claudio Nicoletti

This study shows that FMT from aged mice impairs spatial learning in young recipients by altering hippocampal proteins related to synaptic plasticity and neurotransmission.

Microbiome · Oct 1, 2020Peer-reviewedNeuroscience