Author

Ian M. Fernandes

University Health NetworkORCID 0000-0002-4182-2188Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Beiping QiangiD· 1 shared Blair K. GageiD· 1 shared Dawn BannermaniD· 1 shared Dhana AbdoiD· 1 shared E. Coulter Montague· 1 shared Faisal J. AlibhaiiD· 1 shared Gary SuniD· 1 shared Geoffrey Pickering· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCell Biology

Beiping QiangORCID

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Author profile →

3 papers

Recent·Most cited

Growth Factor-Based Manufacturing of Human Pluripotent Stem Cell-Derived Cardiomyocytes Using the Vertical Wheel Bioreactor System

Faisal J. Alibhai, Tamilla Valdman Sadikov, E. Coulter Montague, Lorena V. Cortés-Medina, Ian M. Fernandes, Gary Sun, Juliana Gomez-Garcia, Harriet W. Chung, Omar Mourad, Beiping Qiang, Sara Santana Nunes, Gordon Keller, Michael A. Laflamme

This paper develops a scalable bioreactor-based method using growth factors to produce human pluripotent stem cell-derived cardiomyocytes with high purity and yield.

Stem Cell Research & Therapy · Sep 3, 2026Peer-reviewedCell Biology

Epicardial extracellular vesicles modulate gene expression following ischemia-reperfusion injury in heart-on-a-chip

Karl T. Wagner, Dawn Bannerman, Qinghua Wu, Simon Pascual‐Gil, Ian M. Fernandes, Luis Felipe Jiménez Vargas, Shuo Yan, Ramak Khosravi, Sargol Okhovatian, Dhana Abdo, Milica Radisic

The paper investigates how epicardial extracellular vesicles affect gene expression during ischemia-reperfusion injury using a heart-on-a-chip model.

Materials Today Bio · May 15, 2026Peer-reviewedBioengineering

Generation of functional vasculature from engraftable human pluripotent stem cell-derived progenitors

Ian M. Fernandes, Hao Yin, Yuan Yao, Blair K. Gage, Zengxuan Nong, Mark Gagliardi, Molly Sandra Shoichet, Geoffrey Pickering, Gordon M. Keller

This paper generates engraftable vascular progenitors from human pluripotent stem cells that form functional vessels and improve perfusion in ischemic tissue.

bioRxiv · May 15, 2026 · PreprintCell Biology