Author

Faisal J. Alibhai

University Health NetworkORCID 0000-0002-8145-4682Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Michael A. LaflammeiD· 4 shared Cristina H. AmoniD· 2 shared David A. RomeroiD· 2 shared Julia E.S. Bauer· 2 shared Amine MazineiD· 1 shared Amirmahdi MostofinejadiD· 1 shared Amos A. Lim· 1 shared Beiping QiangiD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersCell Biology

Michael A. LaflammeORCID

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Author profile →

4 papers

Recent·Most cited

Growth Factor-Based Manufacturing of Human Pluripotent Stem Cell-Derived Cardiomyocytes Using the Vertical Wheel Bioreactor System

Faisal J. Alibhai, Tamilla Valdman Sadikov, E. Coulter Montague, Lorena V. Cortés-Medina, Ian M. Fernandes, Gary Sun, Juliana Gomez-Garcia, Harriet W. Chung, Omar Mourad, Beiping Qiang, Sara Santana Nunes, Gordon Keller, Michael A. Laflamme

This paper develops a scalable bioreactor-based method using growth factors to produce human pluripotent stem cell-derived cardiomyocytes with high purity and yield.

Stem Cell Research & Therapy · Sep 3, 2026Peer-reviewedCell Biology

In Silico ModeIling of Shear Stress and Energy Dissipation Rate Effects on Human Pluripotent Stem Cell Proliferation in Vertical-Wheel Bioreactors

Ferdinand Avikpe, Faisal J. Alibhai, David A. Romero, Amirmahdi Mostofinejad, Julia E.S. Bauer, Coulter Montague, Michael A. Laflamme, Cristina H. Amon

This study develops and validates a mathematical model to predict hPSC proliferation in vertical-wheel bioreactors by incorporating shear stress and energy dissipation rate effects, achieving accurate predictions with low error rates.

bioRxiv · Apr 26, 2026 · PreprintBioengineering

Scaling-Up Vertical-Wheel Bioreactors Based on Cell Aggregate Exposure to Shear Stress and Energy Dissipation Rate

Julia E.S. Bauer, Faisal J. Alibhai, Pouyan Vatani, David A. Romero, Michael A. Laflamme, Cristina H. Amon

This paper characterizes the hydrodynamic environment in vertical-wheel bioreactors and shows that trajectory-based energy dissipation rate exposures better predict cell behavior than volume-averaged metrics.

Annals of Biomedical Engineering · Apr 14, 2026Peer-reviewedBioengineering

Single-cell transcriptome analysis reveals CD34 as a novel marker of human sinoatrial node pacemaker cardiomyocytes

Amos A. Lim, Delaram Pouyabahar, Mishal Ashraf, Kate Huang, Michelle Lohbihler, Brandon M. Murareanu, Matthew L. Chang, Maggie Kwan, Faisal J. Alibhai, Thinh Huy Tran, Amine Mazine, Michael A. Laflamme, Gary D. Bader, Zachary Laksman, Stephanie I. Protze

Nature Communications · Nov 27, 2024Peer-reviewedCell Biology