Author

Ghada Alsaleh

University of OxfordORCID 0000-0002-4211-3420Unclaimed ORCID profile · follow to get notified of new preprints

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Ghada Alsaleh1 paper

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Anna Katharina SimoniD· 3 shared Amir Hossein KayvanjooiD· 1 shared Ana Victoria Lechuga‐ViecoiD· 1 shared Daniel James WilkinsoniD· 1 shared Eleanor J. JonesiD· 1 shared Felix Clemens RichteriD· 1 shared Fiona M. PowrieiD· 1 shared Hanlin Zhang· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

Anna Katharina SimonORCID

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3 papers

Recent·Most cited

ImmunologyAging CellPeer-reviewedJan 12, 2026

Rapamycin exerts its geroprotective effects in the ageing human immune system by enhancing resilience against DNA damage

Loren Kell, Eleanor J. Jones, Nima Gharahdaghi…·Ghada Alsaleh

This study shows that rapamycin improves genome stability in aged human immune cells by reducing DNA damage, enhancing cell survival, and decreasing senescence markers.

13 citationstop 1%

humanproteomics

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Cell BiologyNature CommunicationsPeer-reviewedOct 17, 2025

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling

Klara Piletič, Amir Hossein Kayvanjoo, Felix Clemens Richter…·Anna Katharina Simon

This study shows that autophagy in adipocytes limits obesity-related fibrosis by controlling purine nucleoside metabolism and macrophage polarization.

10 citations

mouseexperimental assay

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Cell BiologybioRxivPreprintDec 12, 2018

Translational control of TFEB and autophagy via eIF5A rejuvenates B cell immunity

Hanlin Zhang, Ghada Alsaleh, Jack Feltham…·Anna Katharina Simon

This study identifies a mechanism by which spermidine regulates autophagy through eIF5A-mediated TFEB translation, improving B cell immunity in aging.

DOI 10.1101/360503

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