Author

Alejandro Matía

Chan Zuckerberg Biohub San FranciscoORCID 0000-0002-4246-5135Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

Carolina AriasiD· 2 shared Ruth HüttenhainiD· 2 shared Ali AkguliD· 1 shared Anil SingapuriiD· 1 shared Astrid Anaya· 1 shared Christopher M. BarkeriD· 1 shared Duo PengiD· 1 shared Hunter O. WoosleyiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Carolina AriasORCID

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Author profile →

3 papers

Recent·Most cited

Human iPSC-derived neurons identify West Nile virus neuropathogenesis signatures and reveal strain-dependent neuroattenuation

Alejandro Matía, Astrid Anaya, Ali Akgul, Anil Singapuri, Sunny Lee, Jinzhao Wang, Ngan Wagoner, Marius Wernig, Thomas Christian Südhof, Christopher M. Barker, Michael Diamond, Carolina Arias, Ruth Hüttenhain

The paper uses human iPSC-derived neurons to study WNV effects, identifying strain-specific neuroattenuation and pathogenic signatures not seen in conventional cell lines.

bioRxiv · Sep 24, 2026 · PreprintMicrobiology

V-SWITCH: A single-vector OFF-to-ON fluorescent reporter of live RNA virus infections

Miguel Cid-Rosas, Michelle E. Grunberg, Alejandro Matía, See-Chi Lee, Hunter O. Woosley, Soorya Pradeep, Shivali Kanwar, Sudip Khadka, Shalin B. Mehta, Ruth Hüttenhain, Vincent Turon‐Lagot, Carolina Arias

V-SWITCH is a fluorescent reporter that detects viral infections by switching from OFF to ON fluorescence, enabling live-cell tracking and screening for antiviral strategies.

bioRxiv · Apr 9, 2026 · PreprintMicrobiology

MaGplotR: a software for the analysis and visualization of multiple MaGeCK screen datasets through aggregation

Alejandro Matía, Marı́a M. Lorenzo, Duo Peng

MaGplotR aggregates and visualizes multiple CRISPR screen datasets to identify common hits and generate publication-quality plots.

bioRxiv · Jan 12, 2023 · PreprintBioinformatics