Carolina Arias

Human iPSC-derived neurons identify West Nile virus neuropathogenesis signatures and reveal strain-dependent neuroattenuation

The paper uses human iPSC-derived neurons to study WNV effects, identifying strain-specific neuroattenuation and pathogenic signatures not seen in conventional cell lines.

A multimodal perturbation atlas defines the phenotypic resolution of cellular morphology.

The paper presents a multimodal perturbation atlas using CRISPR knockouts in A549 cells, combining microscopy, phase imaging, and scRNA-seq to assess phenotypic resolution.

V-SWITCH: A single-vector OFF-to-ON fluorescent reporter of live RNA virus infections

V-SWITCH is a fluorescent reporter that detects viral infections by switching from OFF to ON fluorescence, enabling live-cell tracking and screening for antiviral strategies.

Human RIG-I deficiency confers susceptibility to Kaposi Sarcoma via loss of latency control

This study identifies RIG-I deficiency as a cause of classic Kaposi sarcoma by impairing control of KSHV infection and reactivation.

Robust virtual staining of landmark organelles

The paper develops robust virtual staining methods for cellular landmarks using deep learning, showing improved performance across cell types and imaging conditions.

A Scalable, Easy-to-Deploy, Protocol for Cas13-Based Detection of SARS-CoV-2 Genetic Material

This paper presents a scalable, easy-to-deploy protocol for detecting SARS-CoV-2 genetic material using Cas13-based technology paired with PCR and low-cost instrumentation.

A Fast and Accessible Method for the Isolation of RNA, DNA, and Protein to Facilitate the Detection of SARS-CoV-2

PEARL is a fast, low-cost method for isolating RNA, DNA, and proteins to detect SARS-CoV-2 without commercial kits.