Sohei Tasaki

Migrating mesoderm cells self-organize into a dynamic meshwork structure during chick gastrulation

The paper shows mesoderm cells form a dynamic meshwork during chick gastrulation, supported by N-cadherin adhesion, which facilitates collective migration.

scEGOT: Single-cell trajectory inference framework based on entropic Gaussian mixture optimal transport

scEGOT is a single-cell trajectory inference framework that identifies cell populations and segregation events in time-series scRNA-seq data, revealing key transcription factors involved in PGCLC differentiation.

Nutrient-driven dedifferentiation of enteroendocrine cells promotes adaptive intestinal growth

The paper shows nutrient fluctuations induce dedifferentiation of enteroendocrine cells into intestinal stem cells in Drosophila, promoting adaptive intestinal growth.