Marion I. Stunault

The paper shows the ketogenic diet reduces excitatory synaptic gain by shrinking synaptic vesicle pools through transcriptional and epigenetic changes in the hippocampus.

This study shows that pyruvate supports neuronal viability without glucose and that mitochondrial pyruvate uptake regulates synaptic transmission in hippocampal terminals.

The paper shows that mitochondria, not glycolysis, regulate vesicle release probability and location in hippocampal synapses, and that mitochondrial inhibition increases ultrafast endocytosis.

This study shows that Sirt3 is induced during glucose deprivation and supports synaptic transmission by enhancing mitochondrial function and synaptic vesicle recycling.