Author

Jasmin Sponagel

Washington University in St. LouisORCID 0000-0002-2848-4276Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Ghazaleh AshrafiiD· 2 shared Marion I. StunaultiD· 2 shared Vitaly A. KlyachkoiD· 2 shared Amelia J Barfield· 1 shared Anjali YadaviD· 1 shared Anupama TiwariiD· 1 shared Arsalan HashemiaghdamiD· 1 shared Benjamin A. GarciaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Ghazaleh AshrafiORCID

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2 papers

Recent·Most cited

Ketogenic diet dampens excitatory neurotransmission by shrinking synaptic vesicle pools

Marion I. Stunault, Pan-Yue Deng, Anjali Yadav, Erica M. Periandri, Francisca N. de Luna Vitorino, Michael B Thomsen, Jasmin Sponagel, Amelia J Barfield, Renzelle J. Ponce, Layla Foroughi, Benjamin A. Garcia, Gabor Egervári, Vitaly A. Klyachko, Ghazaleh Ashrafi

The paper shows the ketogenic diet reduces excitatory synaptic gain by shrinking synaptic vesicle pools through transcriptional and epigenetic changes in the hippocampus.

Cell Reports · Feb 1, 2026Peer-reviewedNeuroscience

Mitochondrial pyruvate transport regulates presynaptic metabolism and neurotransmission

Anupama Tiwari, Jongyun Myeong, Arsalan Hashemiaghdam, Hao Zhang, Xianfeng Niu, Marissa A. Laramie, Marion I. Stunault, Jasmin Sponagel, Gary J. Patti, Leah P. Shriver, Vitaly A. Klyachko, Ghazaleh Ashrafi

This study shows that pyruvate supports neuronal viability without glucose and that mitochondrial pyruvate uptake regulates synaptic transmission in hippocampal terminals.

Science Advances · Nov 15, 2024Peer-reviewedNeuroscience