Author

Jongyun Myeong

Washington University in St. LouisORCID 0000-0002-7900-0884Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:imaging· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Vitaly A. KlyachkoiD· 4 shared Ghazaleh AshrafiiD· 2 shared Marion I. StunaultiD· 2 shared Anupama TiwariiD· 1 shared Arsalan HashemiaghdamiD· 1 shared Gary J. PattiiD· 1 shared Gerardo MalagóniD· 1 shared Hao Zhang· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersNeuroscience

Vitaly A. KlyachkoORCID

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4 papers

Recent·Most cited

Astrocytic Cholesterol Fine-Tunes the Balance of Different Modes of Synaptic Exo- and Endocytosis

Jongyun Myeong, Vitaly A. Klyachko

This study shows astrocytic cholesterol regulates synaptic exo- and endocytosis balance by modulating release modes and spatial organization.

bioRxiv · Feb 7, 2026 · PreprintNeuroscience

Mitochondrial pyruvate transport regulates presynaptic metabolism and neurotransmission

Anupama Tiwari, Jongyun Myeong, Arsalan Hashemiaghdam, Hao Zhang, Xianfeng Niu, Marissa A. Laramie, Marion I. Stunault, Jasmin Sponagel, Gary J. Patti, Leah P. Shriver, Vitaly A. Klyachko, Ghazaleh Ashrafi

This study shows that pyruvate supports neuronal viability without glucose and that mitochondrial pyruvate uptake regulates synaptic transmission in hippocampal terminals.

Science Advances · Nov 15, 2024Peer-reviewedNeuroscience

Metabolic Regulation of Single Synaptic Vesicle Exo- and Endocytosis in Hippocampal Synapses

Jongyun Myeong, Marion I. Stunault, Vitaly A. Klyachko, Ghazaleh Ashrafi

The paper shows that mitochondria, not glycolysis, regulate vesicle release probability and location in hippocampal synapses, and that mitochondrial inhibition increases ultrafast endocytosis.

Cell Reports · May 1, 2024Peer-reviewedNeuroscience

Two forms of asynchronous release with distinctive spatiotemporal dynamics in central synapses

Gerardo Malagón, Jongyun Myeong, Vitaly A. Klyachko

The paper identifies two distinct subpopulations of asynchronous release events in hippocampal synapses with different spatiotemporal dynamics and endocytic coupling.

eLife · Apr 25, 2023Peer-reviewedNeuroscience