Author

F. Phil Brooks

Harvard UniversityORCID 0000-0002-4334-8192Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:imaging· 3 Organism:mouse· 3 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam E. CoheniD· 4 shared Hunter C. DavisiD· 3 shared J. David Wong-CamposiD· 2 shared Yitong Qi· 2 shared Benjamin GmeineriD· 1 shared Bill JiaiD· 1 shared Blox BloxhamiD· 1 shared Byung Hun LeeiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersNeuroscience

Adam E. CohenORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Luminos: open-source software for bidirectional microscopy

Daniel G. Itkis, F. Phil Brooks, Hunter C. Davis, Raphael Hotter, J. David Wong-Campos, Yitong Qi, Bill Jia, Madeleine R. Howell, Marley Xiong, Rebecca Frank Hayward, Byung Hun Lee, Yangdong Wang, Rebecca T. Perelman, Adam E. Cohen

Luminos is an open-source MATLAB library for bidirectional microscopy that enables precise synchronization of stimulation, imaging, and experimental parameters.

bioRxiv · Feb 22, 2025 · PreprintBioengineering

Photophysics-informed two-photon voltage imaging using FRET-opsin voltage indicators

F. Phil Brooks, Daozheng Gong, Hunter C. Davis, Pojeong Park, Yitong Qi, Adam E. Cohen

The paper investigates the photophysics of FRET-opsin voltage indicators and demonstrates two-photon voltage imaging in live mice using optimized protocols.

Science Advances · Jan 8, 2025Peer-reviewedNeuroscience

Optical constraints on two-photon voltage imaging

F. Phil Brooks, Hunter C. Davis, J. David Wong-Campos, Adam E. Cohen

The paper compares one-photon and two-photon voltage imaging, finding that 2P requires much higher illumination power and faces tradeoffs between noise and tissue damage.

Neurophotonics · Aug 13, 2024Peer-reviewedNeuroscience

Two-photon photoactivated voltage imaging in tissue with an Archaerhodopsin-derived reporter

Miao‐Ping Chien, Daan Brinks, Guilherme Testa-Silva, He Tian, F. Phil Brooks, Yoav Adam, Blox Bloxham, Benjamin Gmeiner, Simon Kheifets, Adam E. Cohen

The paper develops a novel genetically encoded voltage indicator, NovArch, enabling high-resolution voltage imaging in brain tissue with improved sensitivity, background rejection, and time resolution.

Science Advances · May 5, 2021Peer-reviewedNeuroscience