Hunter C. Davis

Luminos is an open-source MATLAB library for bidirectional microscopy that enables precise synchronization of stimulation, imaging, and experimental parameters.

The paper investigates dendritic excitations in CA1 pyramidal neurons, showing how locally generated Na+ spikes drive history-dependent spike back-propagation and influence associative plasticity.

The paper investigates the photophysics of FRET-opsin voltage indicators and demonstrates two-photon voltage imaging in live mice using optimized protocols.

The paper compares one-photon and two-photon voltage imaging, finding that 2P requires much higher illumination power and faces tradeoffs between noise and tissue damage.

The paper measures voltage dynamics in dendrites of mice neurons during synaptic input integration and action potential propagation, finding shared membrane voltage and rate-dependent propagation of back-propagating action potentials.

The paper introduces improved genetically encoded voltage indicators for all-optical electrophysiology, revealing interneuron network dynamics in live mice.