Author
Harvard UniversityORCID 0000-0002-8219-2944Unclaimed ORCID profile · follow to get notified of new preprints
9 papers
Recent·Most cited
Xiang Wu, Byung Hun Lee, Pojeong Park, J. David Wong-Campos, Junjie Xu, Sarah E. Plutkis, Luke D. Lavis, Adam E. Cohen
This study measures the voltage-to-Ca2+ transfer function in hippocampal CA2 pyramidal neurons during behavior and develops a biophysics-inspired model to predict Ca2+ signals from voltage waveforms.
bioRxiv · Jan 21, 2026 · PreprintNeuroscience
Byung Hun Lee, Pojeong Park, Xiang Wu, J. David Wong-Campos, Junjie Xu, Marley Xiong, Yitong Qi, Yi-Chieh Huang, Daniel G. Itkis, Sarah E. Plutkis, Luke D. Lavis, Adam E. Cohen
This study maps dendritic membrane potential dynamics in CA1 neurons during behavior, showing dendritic spikes are driven by back-propagating action potentials and influence spiking outputs and plasticity.
bioRxiv · Jan 3, 2026 · PreprintNeuroscience
Daniel G. Itkis, F. Phil Brooks, Hunter C. Davis, Raphael Hotter, J. David Wong-Campos, Yitong Qi, Bill Jia, Madeleine R. Howell, Marley Xiong, Rebecca Frank Hayward, Byung Hun Lee, Yangdong Wang, Rebecca T. Perelman, Adam E. Cohen
Luminos is an open-source MATLAB library for bidirectional microscopy that enables precise synchronization of stimulation, imaging, and experimental parameters.
bioRxiv · Feb 22, 2025 · PreprintBioengineering
Pojeong Park, J. David Wong-Campos, Daniel G. Itkis, Byung Hun Lee, Yitong Qi, Hunter C. Davis, Benjamin Antin, Amol Pasarkar, Jonathan B. Grimm, Sarah E. Plutkis, Katie L. Holland, Liam Paninski, Luke D. Lavis, Adam E. Cohen
The paper investigates dendritic excitations in CA1 pyramidal neurons, showing how locally generated Na+ spikes drive history-dependent spike back-propagation and influence associative plasticity.
Nature Communications · Feb 4, 2025Peer-reviewedNeuroscience
F. Phil Brooks, Hunter C. Davis, J. David Wong-Campos, Adam E. Cohen
The paper compares one-photon and two-photon voltage imaging, finding that 2P requires much higher illumination power and faces tradeoffs between noise and tissue damage.
Neurophotonics · Aug 13, 2024Peer-reviewedNeuroscience
J. David Wong-Campos, Pojeong Park, Hunter C. Davis, Yitong Qi, He Tian, Daniel G. Itkis, Do‐Yeon Kim, Jonathan B. Grimm, Sarah E. Plutkis, Luke D. Lavis, Adam E. Cohen
The paper measures voltage dynamics in dendrites of mice neurons during synaptic input integration and action potential propagation, finding shared membrane voltage and rate-dependent propagation of back-propagating action potentials.
bioRxiv · May 25, 2023 · PreprintNeuroscience
Bill Jia, Yitong Qi, J. David Wong-Campos, Sean G. Megason, Adam E. Cohen
The paper identifies a bioelectrical phase transition as the mechanism initiating the first heartbeat in zebrafish, using optogenetic perturbations and all-optical electrophysiology.
bioRxiv · Dec 6, 2022 · PreprintDevelopmental Biology
Andrew T. Landau, Pojeong Park, J. David Wong-Campos, He Tian, Adam E. Cohen, Bernardo Luis Sabatini
The paper shows that specific dendritic branches in cortical layer 2/3 pyramidal cells fail to evoke calcium influx from bAPs due to branch-specific properties, despite having functional VGCCs.
eLife · Mar 23, 2022Peer-reviewedNeuroscience
He Tian, Hunter C. Davis, J. David Wong-Campos, Linlin Z. Fan, Benjamin Gmeiner, Shahinoor Begum, Christopher A. Werley, Gabriel B. Borja, Hansini Upadhyay, Himali Shah, Jane Jacques, Pojeong Park, Yitong Qi, Vicente Parot, Karl A. Deisseroth, Adam E. Cohen
The paper introduces improved genetically encoded voltage indicators for all-optical electrophysiology, revealing interneuron network dynamics in live mice.
bioRxiv · Nov 22, 2021 · PreprintNeuroscience