Daniel G. Itkis

The paper develops a high-throughput all-optical platform to map gene perturbations to electrophysiology using engineered hiPSCs and automated analysis.

This study maps dendritic membrane potential dynamics in CA1 neurons during behavior, showing dendritic spikes are driven by back-propagating action potentials and influence spiking outputs and plasticity.

Luminos is an open-source MATLAB library for bidirectional microscopy that enables precise synchronization of stimulation, imaging, and experimental parameters.

The paper investigates dendritic excitations in CA1 pyramidal neurons, showing how locally generated Na+ spikes drive history-dependent spike back-propagation and influence associative plasticity.

The paper measures voltage dynamics in dendrites of mice neurons during synaptic input integration and action potential propagation, finding shared membrane voltage and rate-dependent propagation of back-propagating action potentials.