Author

Peter A. Sehr

European Molecular Biology LaboratoryORCID 0000-0002-4348-5066Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Alessandra MagistratoiD· 1 shared David William Will· 1 shared Eva KowalinskiiD· 1 shared Ignacio Enrique SancheziD· 1 shared Iven Hollmer· 1 shared Jana AupičiD· 1 shared Janosch HennigiD· 1 shared Joe LewisiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Alessandra MagistratoORCID

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2 papers

Recent·Most cited

Electrostatic interactions compensate energetic frustration in the coupled folding and binding of intrinsically disordered proteins

Lucı́a Álvarez, Nicolás A. Garrone, Michaël Claron, Kristian Schweimer, Juliana Glavina, David William Will, Peter A. Sehr, Joe Lewis, Toby J. Gibson, Ignacio Enrique Sanchez, Janosch Hennig, Lucia Beatriz Chemes

The paper investigates the energy landscape of coupled folding and binding in intrinsically disordered proteins, finding that electrostatic interactions compensate for energetic frustration.

bioRxiv · Jun 23, 2026 · PreprintBiophysics

Recognition and catalytic mechanism of tRNA m3C methyltransferase METTL6

Jana Aupič, Iven Hollmer, Laura Tengo, Peter A. Sehr, Eva Kowalinski, Alessandra Magistrato

This study defines the mechanism by which METTL6 and SerRS cooperatively recognize and catalyze tRNA m3C methylation using simulations and in vitro experiments.

bioRxiv · Jun 25, 2025 · PreprintBiochemistry