Author

Martin S. Tallman

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-4367-6102Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:whole-exome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:GWAS / association mapping· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Ross L. LevineiD· 3 shared Ahmet ZehiriD· 2 shared Marc LadanyiiD· 2 shared Maria E. ArcilaiD· 2 shared Mariko YabeiD· 2 shared Michael F. BergeriD· 2 shared Ryan N. PtashkiniD· 2 shared Ryma BenayediD· 2 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersSystems Biology

Ross L. LevineORCID

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3 papers

Recent·Most cited

Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes

B. Bishal Paudel, Su‐Fern Tan, Todd E. Fox, Johnson Ung, Upendarrao Golla, Jeremy J.P. Shaw, Wendy Dunton, Irene Lee, Wisam A. Fares, Satyam Patel, Arati K. Sharma, Aaron D. Viny, Brian M. Barth, Martin S. Tallman, Myles C. Cabot, , Thomas P. Loughran

This study identifies two sphingolipidomic subtypes in AML, with one subtype associated with poor clinical outcomes and high-risk features.

Blood Advances · Jan 3, 2024Peer-reviewedSystems Biology

Enhanced clinical assessment of hematologic malignancies through routine paired tumor:normal sequencing

Ryan N. Ptashkin, Mark David Ewalt, Gowtham Jayakumaran, Iwona J Kiecka, Anita S. Bowman, JinJuan Yao, Jacklyn Casanova, Yun-Te David Lin, Kseniya Petrova‐Drus, Abhinita S. Mohanty, Ruben Bacares, Jamal K. Benhamida, Satshil Rana, Разумова Анна Ивановна, Chad Vanderbilt, , Maria E. Arcila

This study presents a paired tumor:normal sequencing dataset for hematologic malignancies, showing improved identification of somatic variants and their clinical relevance.

medRxiv · Oct 3, 2022 · PreprintGenetic & Genomic Medicine

Oncologic Therapy Shapes the Fitness Landscape of ClonalHematopoiesis

Kelly L. Bolton, Ryan N. Ptashkin, Teng Gao, Lior Zvi Braunstein, Sean M. Devlin, Daniel John Kelly, Minal A. Patel, Antonin Berthon, Aijazuddin Syed, Mariko Yabe, Catherine Callaghan Coombs, Nicole M. Caltabellotta, Mike Walsh, Kenneth Offit, Zsofia Kinga Stadler, , Elli Papaemmanuil

The paper shows oncologic therapy increases clonal hematopoiesis with DDR mutations, which predicts risk of therapy-related myeloid neoplasms.

bioRxiv · Nov 20, 2019 · PreprintGenetics