Author

Wisam A. Fares

University of Virginia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:machine learning (classical)· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Kevin A. JanesiD· 2 shared Aaron D. VinyiD· 1 shared Arati K. SharmaiD· 1 shared B. Bishal PaudeliD· 1 shared Brant E. IsaksoniD· 1 shared Brian M. BarthiD· 1 shared David F. ClaxtoniD· 1 shared David J. FeithiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersSystems Biology

Kevin A. JanesORCID

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Author profile →

3 papers

Recent·Most cited

Multimodal analysis identifies pericyte-centered signaling programs altered by sex and brain region in Alzheimer's Disease

Kareem El‐Ghazawi, Yonathan Tamrat Aberra, Yashasvisai Veeramasu, Wisam A. Fares, Brant E. Isakson, Harald W. Sontheimer, Ukpong B. Eyo, SHAYN M. PEIRCE

The paper identifies sex- and brain region-specific pericyte signaling changes in Alzheimer's Disease using single-nucleus RNA sequencing and spatial transcriptomics.

Communications Biology · Jun 8, 2026Peer-reviewedBioinformatics

TGFβ signaling systems are prone to inhibition and ligand competition by coreceptor

Wisam A. Fares, Kevin A. Janes

The paper shows coreceptors inhibit TGFβ signaling more often than they promote it, altering ligand perception through competition in multi-ligand systems.

bioRxiv · Mar 3, 2026 · PreprintSystems Biology

Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes

B. Bishal Paudel, Su‐Fern Tan, Todd E. Fox, Johnson Ung, Upendarrao Golla, Jeremy J.P. Shaw, Wendy Dunton, Irene Lee, Wisam A. Fares, Satyam Patel, Arati K. Sharma, Aaron D. Viny, Brian M. Barth, Martin S. Tallman, Myles C. Cabot, , Thomas P. Loughran

This study identifies two sphingolipidomic subtypes in AML, with one subtype associated with poor clinical outcomes and high-risk features.

Blood Advances · Jan 3, 2024Peer-reviewedSystems Biology