Mattia Bernetti

This study investigates the RAD51-BRC repeats interaction using computational and experimental methods to better understand its role in homologous recombination and its implications for cancer.

This study uses integrative ensemble modeling to identify RNA conformations that can be targeted by small molecules, revealing ligandable sites not visible in static structures.

The paper evaluates a structure-based drug discovery pipeline for targeting MALAT1 using 21 ligands, identifying a binding mode that aligns with experimental affinity trends.

This study combines computational and experimental methods to characterize the conformational dynamics of the RAD51-BRC4 complex, revealing key residues involved in their interaction.