Author

Ralf Fliegert

University Medical Center Hamburg-EppendorfORCID 0000-0002-4374-673XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:biophysical modeling· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Andreas H. GuseiD· 1 shared Frederike Kulow· 1 shared Henning TidowiD· 1 shared Lucas A. DefelipeiD· 1 shared María García-AlaiiD· 1 shared Michael ZimmermanniD· 1 shared Shivansh GoyaliD· 1 shared Stefanie EtzoldiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiophysics

Andreas H. GuseORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Domain-Specific Agonist Binding Affinities Explain Structural and Functional Regulation of TRPM2

Tatiana Kupriianova, Tessa Schwarzer, Thorben Thalacker, Lucas A. Defelipe, Stefanie Etzold, Frederike Kulow, Vanessa Pahl, Shivansh Goyal, Vanna Nguyen, Michael Zimmermann, Andreas H. Guse, Xiaolu A. Cambronne, Henning Tidow, Ralf Fliegert, María García-Alai

This study quantifies the binding affinities of TRPM2 domains for ADPR analogs and shows that MHR1/2 drives activation while NUDT9H maintains structural integrity.

bioRxiv · Apr 1, 2026 · PreprintBiophysics