Author

Shivansh Goyal

The University of Texas at AustinORCID 0000-0003-3735-2475Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Vanna NguyeniD· 2 shared Xiaolu A. CambronneiD· 2 shared Andreas H. GuseiD· 1 shared Ciara Fields· 1 shared Frederike Kulow· 1 shared Henning TidowiD· 1 shared Hsin‐Ru Chan· 1 shared Kelton Deloney· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiophysics

Vanna NguyenORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintApr 1, 2026

Domain-Specific Agonist Binding Affinities Explain Structural and Functional Regulation of TRPM2

Tatiana Kupriianova, Tessa Schwarzer, Thorben Thalacker…·María García-Alai

This study quantifies the binding affinities of TRPM2 domains for ADPR analogs and shows that MHR1/2 drives activation while NUDT9H maintains structural integrity.

DOI 10.64898/2026.03.30.715250

humanproteomics

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BiochemistrybioRxivPreprintFeb 9, 2026

Transient signaling of free ADP-ribose monitored with an intracellular biosensor

Shivansh Goyal, Vanna Nguyen, Scott N. Lyons…·Xiaolu A. Cambronne

The paper develops a biosensor to measure intracellular ADP-ribose dynamics and finds that ADPR levels are transient, tunable, and critical for TRPM2 activation.

1 citation

proteomicsexperimental assay

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