Henning Tidow

Capturing transient states of heterodimeric ABC transporter TM287/288 by Time-Resolved Small-Angle X-ray Scattering

This study captures transient states of the ABC transporter TM287/288 using time-resolved small-angle X-ray scattering and reveals a transient occluded state in its ATP-driven conformational cycle.

Domain-Specific Agonist Binding Affinities Explain Structural and Functional Regulation of TRPM2

This study quantifies the binding affinities of TRPM2 domains for ADPR analogs and shows that MHR1/2 drives activation while NUDT9H maintains structural integrity.

Crystal structures of the outer membrane transporter FoxA provide novel insights into TonB-mediated siderophore uptake and signalling

The paper presents crystal structures of the FoxA transporter from Pseudomonas aeruginosa in complex with ferrioxamine B and TonB, revealing the mechanism of siderophore uptake and TonB interaction.