This study identifies proteomic changes in brain-derived extracellular vesicles during tuberculous meningitis, revealing shifts toward inflammation and neuronal injury.

Cells · Sep 25, 2026Peer-reviewedMicrobiology

Profiling miRNAs involved in Human Oligodendrocyte Precursor Cell Differentiation and Maturation

Mansoureh Barzegar, Asmita Dhukhwa, Vaidehi Nilesh Patel, Fernanda Carrizo Velásquez, Samarjit Das, Arun H. Patil, Marc K. Halushka, Donald J. Zack, Xitiz Chamling

The paper identifies stage-specific miRNAs involved in human oligodendrocyte precursor cell differentiation and maturation through miRNA profiling of hESC-derived cells.

Cells · Jul 27, 2026Peer-reviewedNeuroscience

The association of extracellular vesicle (EV)-cargo miR-330-3p with postoperative delirium and a potential mechanism of tau phosphorylation and neuron toxicity

Tomonari Fujimori, Sushmita Chakraborty, Atsushi Miyagawa, Harshita Tak, Atsushi Yamaguchi, Charles W. Jr Hogue, Charles H Brown, Samarjit Das

This paper identifies miR-330-3p as a biomarker for postoperative delirium (POD) after cardiac surgery, showing its association with increased tau phosphorylation and reduced neuronal viability in vitro.

bioRxiv · Apr 1, 2026 · PreprintMolecular Biology

Formate reduces ischemic injury in the male heart by increasing protein S-nitrosation

Haley Garbus, Raihan Kabir, Obialunanma V. Ebenebe, Priyanka Patel, Deepthi Ashok, Diego Quiroga, Samarjit Das, Brian P O'Rourke, Mark J. Crabtree, Mark Jeffrey Kohr

This study shows formate reduces ischemic injury in male hearts by increasing protein S-nitrosation and preserving BH4 levels through a NOS-dependent mechanism.

bioRxiv · Feb 26, 2026 · PreprintPhysiology